Diana Freire, Author at MaxWell Biosystems

MaxWell Monthly Must-Reads | World Organoid Research Day

March 22, 2023

Blog, MaxWell Monthly Must-Reads, Organoids

Today is World Organoid Research Day! Let’s celebrate the incredible advances being made in this fascinating and yet rapidly evolving field of research by raising awareness on the potential of organoids in advancing biomedical research, drug discovery, regenerative medicine, modeling complex diseases, personalized medicine, reducing animal testing, and advancing stem cell research. Grown from human stem cells, organoids are miniaturized three-dimensional structures that closely resemble the architecture and function of real human organs, providing a more complex and comprehensive…

MaxWell Monthly Must-Reads | iPSC as a tool for Disease Cell Modelling

February 21, 2023

Diana Freire

Blog, iPSC, MaxWell Monthly Must-Reads

Welcome to our first MaxWell Monthly Must-Reads blog of 2023! After 2022 – a year full of great scientific advances and discoveries – this month we would like to focus on induced Pluripotent Stem Cells (iPSC) as a great tool for Disease Cell Modelling and for developing novel disease therapies. Development and advancement of patient derived iPSC technology has opened several avenues for scientists to generate relevant and reproducible human in vitro models. iPSC technology has also allowed researchers to…

HyVIS project

December 8, 2021

Diana Freire

Collaboration, Featured, News, Press Release

MaxWell Biosystems Becomes a Key Partner in a €3M EU-Financed Project “HyVIS”: Next Generation Prosthesis for Visual Restoration Hybrid Synapse for Vision (HyVIS) is a project funded by European Union Horizon 2020 FET-OPEN program 1, which aims to combine several technologies to achieve the groundbreaking restoration of synaptic light-mediated input in retinas with impaired photoreceptors, leading to treatments for diseases such as in retinitis pigmentosa and age-related macular degeneration (AMD). The key focus of HyVIS project is the development of an artificial light-sensitive prosthesis,…

HD-MEAs play a role in the functional characterization of human iPSC-derived dopaminergic neurons

June 22, 2021

Diana Freire

Blog, iPSC, MaxOne, News, Publications

Maria Sundberg from the Boston Children’s Hospital, Harvard Medical School, and colleagues, recently reported in Nature Communications a study on the reciprocal copy number variations (CNVs) of 16p11.2 gene region, associated with a wide spectrum of neuropsychiatric and neurodevelopmental disorders. For the functional analysis of the developing iPSC-derived dopaminergic (DA) neuron network, complementary-metal-oxide-semiconductor (CMOS)-based high-density microelectrode arrays (HD-MEAs), MaxOne System by MaxWell Biosystems was extensively used. 16p.11.2 Reciprocal copy number variations (CNVs) in neuropsychiatric disorders 16p.11.2 CNVs have been implicated in…

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