MaxOne Single-Well HD-MEA System

MaxOne High-Density Microelectrode Array (HD-MEA) System

Key Features

High-Quality Data
High-resolution and high-quality data while tracking dynamic changes at cellular, subcellular and network levels.
Sensitivity
Smallest signals capture (uV) thanks to low-noise recording channels and high electrode density.
Flexible
Compactly built, MaxOne Recording Unit can be flexibly installed in various environments and is compatible with other devices for both cultured samples and acute tissues.
Reproducibility
Optimized recordings strategies to analyze the entire culture at individual neuronal levels, increasing data reproducibility and statistical power.
Long-Term Experiments
Cell development, maturation, or compound effects access by performing longitudinal experiments over the course of days, weeks, and months.
Integrity
Non-invasive and label-free recordings, eliminating any potential side effects associated with the use of dyes and prolonged exposure to light.

Product Overview

MaxWell Biosystems’s MaxOne is a CMOS-based HD-MEA, an electrical imaging system for neuroscience, drug discovery, and cell assessment applications. MaxOne captures high-quality signals at subcellular resolution from long-term culture experiments and acute tissue experiments (e.g., brain slices, retina).

Cell Activity Footprint
26’400 Pt-Electrodes Per Well
3’625 Electrodes/mm2
Low-Noise Readouts
Flexible Electrical Stimulation
Different readouts
Network level
Cellular level
Subcellular level

MaxOne HD-MEA system can be flexibly installed in diverse environments. For instance, MaxOne Recording Unit can operate long-term inside cell-culture incubators, and can be integrated with perfusion systems, enabling users to perform acute tissue recordings. Additionally, the system is compatible with other devices, such as being placed under an upright microscope for imaging and microscopy purposes, and integrated with tissue holders for acute tissue experiments.

Learn About MaxOne Accessories

All consumable MaxOne Chips share the same core features of our HD-MEA technology but differs in ways that allows them to be more suitable for cultured or acute samples. 

Learn About MaxOne Chips
MaxOne System Features
ComponentsHub
Recording Unit
System status indicator LED
Dimension (L x W x H)Hub: 18.5 x 28x 9 cm3
Recording Unit: 15 x 9.5 x 2.5 cm3
Chip compatibilitySmall (PSM)
Large (PLM)
Incubator friendlyYes, for the Recording Unit

This might also interest you

MaxTwo Multi-Well HD-MEA System is a high-throughput, high-resolution electrophysiology platform for recording and stimulating electrogenic cells in vitro. MaxTwo combines 6 or 24 MaxOne high-density microelectrode arrays in a multiwell format.
MaxLab Live Software is a comprehensive and user-friendly tool designed for visualizing, recording, and analyzing data recorded with MaxOne and MaxTwo. Its assays guide the user through automated workflows to the extraction of key metrics at multiple levels, including network, single-cell, and subcellular details.

Publications Featuring the MaxOne

68 entries « 1 of 2 »
Mechanical stimulation and electrophysiological monitoring at subcellular resolution reveals differential mechanosensation of neurons within networks

Kasuba, Krishna Chaitanya; Buccino, Alessio Paolo; Bartram, Julian; Gaub, Benjamin M; Fauser, Felix J; Ronchi, Silvia; Kumar, Sreedhar Saseendran; Geissler, Sydney; Nava, Michele M; Hierlemann, Andreas; Müller, Daniel J

Mechanical stimulation and electrophysiological monitoring at subcellular resolution reveals differential mechanosensation of neurons within networks Journal Article

Nature Nanotechnology, 2024.

Abstract | Links | BibTeX

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

Hruska-Plochan, Marian; Wiersma, Vera I; Betz, Katharina M; Mallona, Izaskun; Ronchi, Silvia; Maniecka, Zuzanna; Hock, Eva-Maria; Tantardini, Elena; Laferriere, Florent; Sahadevan, Sonu; Hoop, Vanessa; Delvendahl, Igor; Pérez-Berlanga, Manuela; Gatta, Beatrice; Panatta, Martina; van der Bourg, Alexander; Bohaciakova, Dasa; Sharma, Puneet; Vos, Laura De; Frontzek, Karl; Aguzzi, Adriano; Lashley, Tammaryn; Robinson, Mark D; Karayannis, Theofanis; Mueller, Martin; Hierlemann, Andreas; Polymenidou, Magdalini

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD Journal Article

Nature, 2024.

Abstract | Links | BibTeX

DeePhys: A machine learning–assisted platform for electrophysiological phenotyping of human neuronal networks

Hornauer, Philipp; Prack, Gustavo; Anastasi, Nadia; Ronchi, Silvia; Kim, Taehoon; Donner, Christian; Fiscella, Michele; Borgwardt, Karsten; Taylor, Verdon; Jagasia, Ravi; Roqueiro, Damian; Hierlemann, Andreas; Schröter, Manuel

DeePhys: A machine learning–assisted platform for electrophysiological phenotyping of human neuronal networks Journal Article

Stem Cell Reports, 2024.

Abstract | Links | BibTeX

Protosequences in human cortical organoids model intrinsic states in the developing cortex

van der Molen, Tjitse; Spaeth, Alex; Chini, Mattia; Bartram, Julian; Dendukuri, Aditya; Zhang, Zongren; Bhaskaran-Nair, Kiran; Blauvelt, Lon J; Petzold, Linda R; Hansma, Paul K; Teodorescu, Mircea; Hierlemann, Andreas; Hengen, Keith B; Hanganu-Opatz, Ileana L; Kosik, Kenneth S; Sharf, Tal

Protosequences in human cortical organoids model intrinsic states in the developing cortex Journal Article

bioRxiv, 2023.

Abstract | Links | BibTeX

Brain organoid reservoir computing for artificial intelligence

Cai, Hongwei; Ao, Zheng; Tian, Chunhui; Wu, Zhuhao; Liu, Hongcheng; Tchieu, Jason; Gu, Mingxia; Mackie, Ken; Guo, Feng

Brain organoid reservoir computing for artificial intelligence Journal Article

Nature Electronics, 2023.

Abstract | Links | BibTeX

Internet-Connected Cortical Organoids for Project-Based Stem Cell and Neuroscience Education

Elliott, Matthew A T; Schweiger, Hunter E; Robbins, Ash; Vera-Choqqueccota, Samira; Ehrlich, Drew; Hernandez, Sebastian; Voitiuk, Kateryna; Geng, Jinghui; Sevetson, Jess L; Core, Cordero; Rosen, Yohei M; Teodorescu, Mircea; Wagner, Nico O; Haussler, David; Mostajo-Radji, Mohammed A

Internet-Connected Cortical Organoids for Project-Based Stem Cell and Neuroscience Education Journal Article

eNeuro, 2023.

Abstract | Links | BibTeX

Measuring and Inducing the Plasticity of Single-Neuron Scale at Multiple Points

Kobayashi, Toki; Shimba, Kenta; Kotani, Kiyoshi; Jimbo, Yasuhiko

Measuring and Inducing the Plasticity of Single-Neuron Scale at Multiple Points Conference

ISSS Xplore, 2023.

Abstract | Links | BibTeX

Activity- and Spatial-dependent Variations in Axonal Conduction Recorded from Microtunnel Electrodes

Tamatani, Chie; Shimba, Kenta; andYasuhiko Jimbo, Kiyoshi Kotani

Activity- and Spatial-dependent Variations in Axonal Conduction Recorded from Microtunnel Electrodes Conference

IEEE Xplore, 2023.

Abstract | Links | BibTeX

Driving electrochemical reactions at the microscale using CMOS microelectrode arrays

Duru, Jens; Rüfenacht, Arielle; Löhle, Josephine; Pozzi, Marcello; Forró, Csaba; Ledermann, Linus; Bernardi, Aeneas; Matter, Michael; Renia, André; Simona, Benjamin; Tringides, Christina M; Bernhard, Stéphane; Ihle, Stephan J; Hengsteler, Julian; Maurer, Benedikt; Zhanga, Xinyu; Nakatsuka, Nako

Driving electrochemical reactions at the microscale using CMOS microelectrode arrays Journal Article

Lab on a Chip, 2023, ISSN: 1473-0189.

Abstract | Links | BibTeX

Closed-loop neurostimulation via expression of magnetogenetics-sensitive protein in inhibitory neurons leads to reduction of seizure activity in a rat model of epilepsy

Metto, Abigael C; Telgkamp, Petra; McLane-Svoboda, Autumn K; Gilad, Assaf A; Pelled, Galit

Closed-loop neurostimulation via expression of magnetogenetics-sensitive protein in inhibitory neurons leads to reduction of seizure activity in a rat model of epilepsy Journal Article

Brain Research, 2023.

Abstract | Links | BibTeX

BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network

Levi, Timothee; Beaubois, Romain; Cheslet, Jérémy; Duenki, Tomoya; Khoyratee, Farad; Branchereau, Pascal; Ikeuchi, Yoshiho

BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network Journal Article

Research Square, 2023.

Abstract | Links | BibTeX

Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1mutations

Silverman, Jill L; Fenton, Timothy; Haouchine, Olivia; Hallam, Elizabeth; Smith, Emily; Jackson, Kiya; Rahbarian, Darlene; Canales, Cesar; Adhikari, Anna; Nord, Alex; Ben-Shalom, Roy

Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1mutations Journal Article

Research Square, 2023.

Abstract | Links | BibTeX

Critical dynamics arise during structured information presentation within embodied in vitro neuronal networks

Habibollahi, Forough; Kagan, Brett J; Burkitt, Anthony N; French, Chris

Critical dynamics arise during structured information presentation within embodied in vitro neuronal networks Journal Article

Nature Communications, 2023.

Abstract | Links | BibTeX

Functional imaging of conduction dynamics in cortical and spinal axons

Radivojevic, Milos; Punga, Anna Rostedt

Functional imaging of conduction dynamics in cortical and spinal axons Journal Article

eLife, 2023.

Abstract | Links | BibTeX

Investigation of the input-output relationship of engineered neural networks using high-density microelectrode arrays

Duru, Jens; Maurer, Benedikt; Doran, Ciara Giles; Jelitto, Robert; Küchler, Joël; Ihle, Stephan J; Ruff, Tobias; John, Robert; Genocchi, Barbara; Vörös, János

Investigation of the input-output relationship of engineered neural networks using high-density microelectrode arrays Journal Article

Biosensors and Bioelectronics, 2023.

Abstract | Links | BibTeX

Microfluidic technologies for reconstituting neuronal network functions in vitro

Yamamoto, Hideaki; Hirano-Iwata, Ayumi; Sato, Shigeo

Microfluidic technologies for reconstituting neuronal network functions in vitro Journal Article

JSAP Review, 2023.

Abstract | Links | BibTeX

A CMOS-based highly scalable flexible neural electrode interface

Zhao, Eric T; Hull, Jacob M; Hemed, Nofar Mintz; Ulusan, Hasan; Bartram, Julian; Zhang, Anqi; Wang, Pingyu; Pham, Albert; Silvia Ronchi, John Huguenard R; Hierlemann, Andreas; Melosh, Nicholas A

A CMOS-based highly scalable flexible neural electrode interface Journal Article

Science Advances, 2023.

Abstract | Links | BibTeX

Cultured Vagal Afferent Neurons as Sensors for Intestinal Effector Molecules

Girardi, Gregory; Zumpano, Danielle; Goshi, Noah; Raybould, Helen; Seker, Erkin

Cultured Vagal Afferent Neurons as Sensors for Intestinal Effector Molecules Journal Article

biosensors, 2023.

Abstract | Links | BibTeX

Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking

Bartram, Julian; Franke, Felix; Kumar, Sreedhar Saseendran; Buccino, Alessio Paolo; Xue, Xiaohan; Gänswein, Tobias; Schröter, Manuel; Kim, Taehoon; Kasuba, Krishna Chaitanya; Hierlemann, Andreas

Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking Journal Article

eLife, 2023.

Abstract | Links | BibTeX

Investigation of the input-output relationship of engineered neural networks using high-density microelectrode arrays

Duru, Jens; Maurer, Benedikt; Doran, Ciara Giles; Jelitto, Robert; Küchler, Joël; Ihle, Stephan J; Ruff, Tobias; John, Robert; Genocchi, Barbara; Vörös, János

Investigation of the input-output relationship of engineered neural networks using high-density microelectrode arrays Journal Article

SSRN, 2023.

Abstract | Links | BibTeX

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells

Xu, He Jax; Yao, Yao; Yao, Fenyong; Chen, Jiehui; Li, Meishi; Yang, Xianfa; Li, Sheng; Lu, Fangru; Hu, Ping; He, Shuijin; Peng, Guangdun; Jing, Naihe

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells Journal Article

Cell Regeneration, 2023.

Abstract | Links | BibTeX

Functional imaging of conduction dynamics in cortical and spinal axons

Radivojevic, Milos; Punga, Anna Rostedt

Functional imaging of conduction dynamics in cortical and spinal axons Journal Article

BioRxiv, 2023.

Abstract | Links | BibTeX

Brain Organoid Computing for Artificial Intelligence

Cai, Hongwei; Ao, Zheng; Tian, Chunhui; Wu, Zhuhao; Liu, Hongcheng; Tchieu, Jason; Gu, Mingxia; Mackie, Ken; and Guo, Feng

Brain Organoid Computing for Artificial Intelligence Journal Article

bioRxiv, 2023.

Abstract | Links | BibTeX

A Neurospheroid-Based Microrobot for Targeted Neural Connections in a Hippocampal Slice

Kim, Eunhee; Jeon, Sungwoong; Yang, Yoon-Sil; Jin, Chaewon; Kim, Jin-young; Oh, Yong- Seok; Rah, Jong-Cheol; and Choi, Hongsoo

A Neurospheroid-Based Microrobot for Targeted Neural Connections in a Hippocampal Slice Journal Article

Advanced Materials, 2023.

Abstract | Links | BibTeX

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks

Sato, Yuya; Yamamoto, Hideaki; Kato, Hideyuki; Tanii, Takashi; Sato, Shigeo; Hirano-Iwata, Ayumi

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks Journal Article

Frontiers in Neuroscience, 2023.

Abstract | Links | BibTeX

A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

Han, Xiaobo; Matsuda, Naoki; Ishibashi, Yuto; Odawara, Aoi; Takahashi, Sayuri; Tooi, Norie; Kinoshita, Koshi; Suzuki, Ikuro

A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement Journal Article

Biomaterials Research, 2022.

Abstract | Links | BibTeX

Generation of Human Striatal-Midbrain Assembloids From Human Pluripotent Stem Cells to Model Alpha-Synuclein Propagation

Tran, Hoang-Dai; Shin, Min-Kyoung; Denman, Charlotte; Han, Run-Run; Kuhn, Bernd; Arbuthnott, Gordon; Jo, Junghyun

Generation of Human Striatal-Midbrain Assembloids From Human Pluripotent Stem Cells to Model Alpha-Synuclein Propagation Journal Article

Sneak Peek - Cell Press, 2022.

Abstract | Links | BibTeX

Homophilic wiring principles underpin neuronal network topology in vitro

Akarca, Danyal; Dunn, Alexander W E; Hornauer, Philipp J; Ronchi, Silvia; Fiscella, Michele; Wang, Congwei; Terrigno, Marco; Jagasia, Ravi; Vértes, Petra E; Mierau, Susanna B; Paulsen, Ole; Eglen, Stephen J; Hierlemann, Andreas; Astle, Duncan E; Schröter, Manuel

Homophilic wiring principles underpin neuronal network topology in vitro Journal Article

BioRxiv, 2022.

Abstract | Links | BibTeX

Biological Neurons vs Deep Reinforcement Learning: Sample efficiency in a simulated game-world

Habibollahi, Forough; Khajehnejad, Moein; Gaurav, Amitesh; Kagan, Brett Joseph

Biological Neurons vs Deep Reinforcement Learning: Sample efficiency in a simulated game-world Conference

2022.

Abstract | Links | BibTeX

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons

McSweeney, Danny; Gabriel, Rafael; Jin, Kang; Pang, Zhiping P; Aronow, Bruce; and Pak, ChangHui

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons Journal Article

iScience, 2022.

Abstract | Links | BibTeX

In vitro neurons learn and exhibit sentience when embodied in a simulated game-world

Kagan, Brett J; Kitchen, Andy C; Tran, Nhi T; Habibollahi, Forough; Khajehnejad, Moein; Parker, Bradyn J; Bhat, Anjali; Rollo, Ben; Razi, Adeel; Friston, Karl J

In vitro neurons learn and exhibit sentience when embodied in a simulated game-world Journal Article

Neuron, 2022.

Abstract | Links | BibTeX

Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays

Habibey, Rouhollah; Striebel, Johannes; Schmieder, Felix; Czarske, Jürgen; Busskamp, Volker

Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays Journal Article

Frontiers in Neuroscience, 2022.

Abstract | Links | BibTeX

Repeated and On-Demand Intracellular Recordings of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

Lee, Jihyun; Gänswein, Tobias; Ulusan, Hasan; Emmenegger, Vishalini; Saguner, Ardan M; Duru, Firat; and Hierlemann, Andreas

Repeated and On-Demand Intracellular Recordings of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells Journal Article

ACS Sensors, 2022.

Abstract | Links | BibTeX

Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus

Al-Absi, Abdel-Rahman; Thambiappaa, Sakeerthi Kethees; Khanc, Ahmad Raza; Glerup, Simon; Sanchez, Connie; Landau, Anne M; Nyengaard, Jens R

Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus Journal Article

Molecular and Cellular Neuroscience, 2022.

Abstract | Links | BibTeX

A multi-modal fitting approach to construct single-neuron models with patch clamp and high-density microelectrode arrays

Buccino Alessio Paolo; Damart, Tanguy; Bartram Julian; Mandge Darshan; Xue Xiaohan; Zbili Mickael; Gänswein Tobias; Jaquier Aurélien; Emmenegger Vishalini; Markram Henry; Hierlemann Andreas; Van Geit Werner.

A multi-modal fitting approach to construct single-neuron models with patch clamp and high-density microelectrode arrays Journal Article

bioRxiv, 2022.

Abstract | Links | BibTeX

Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking

Xue, Xiaohan; Buccino, Alessio Paolo; Kumar, Sreedhar Saseendran; Hierlemann, Andreas; Bartram, Julian

Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking Journal Article

Journal of Neural Engineering, 2022.

Abstract | Links | BibTeX

Functional neuronal circuitry and oscillatory dynamics in human brain organoids

Sharf Tal; Molen, Tjitse; Glasauer Stella; Guzman Elmer; Buccino Alessio; Luna Gabriel; Cheng Zhuowei; Audouard Morgane; Ranasinghe Kamalini; Kudo Kiwamu; Nagarajan Srikantan; Tovar Kenneth; Petzold Linda; Hierlemann Andreas; Hansma Paul; ; Kosik, Kenneth;

Functional neuronal circuitry and oscillatory dynamics in human brain organoids Journal Article

Nature Communications, 2022.

Abstract | Links | BibTeX

Suppression without inhibition: how retinal computation contributes to saccadic suppression

Idrees, Saad; Baumann, Matthias-Philipp; Korympidou, Maria M; Schubert, Timm; Kling, Alexandra; Franke, Katrin; Hafed, Ziad M; Franke, Felix; Münch, Thomas A

Suppression without inhibition: how retinal computation contributes to saccadic suppression Journal Article

Communications Biology, 2022.

Abstract | Links | BibTeX

Functional imaging of brain organoids using high-density microelectrode arrays

Schröter Manuel; Wang, Congwei; Terrigno Marco; Hornauer Philipp; Huang Ziqiang; Jagasia Ravi; Hierlemann Andreas

Functional imaging of brain organoids using high-density microelectrode arrays Journal Article

MRS Bulletin, 2022.

Abstract | Links | BibTeX

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells

Xu, Jax H; Yao, Yao; Yao, Fenyong; Chen, Jiehui; Li, Meishi; Xianfa, ; Yang, ; Li, Sheng; Lu, Fangru; Hu, Ping; He, Shuijin; Peng, Guangdun; Jing, Naihe

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells Journal Article

BioRxiv, 2022.

Abstract | Links | BibTeX

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons

Sommer Daniel ; Rajkumar, Sandeep; Seidel Mira; Aly Amr; Ludolph Albert; Ho Ritchie; Boeckers Tobias; Catanese Alberto.

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons Journal Article

Frontiers in Molecular Neuroscience, 2022.

Abstract | Links | BibTeX

Automated detection of extracellular action potentials from single neurons

Cheng, Zhuowei; Guzman, Elmer; van der Molen, Tjitse; Sharf, Tal; Hansma, Paul K; Kosik, Kenneth S; Petzold, Linda; Tovar, Kenneth R

Automated detection of extracellular action potentials from single neurons Journal Article

bioRxiv, 2022.

Abstract | Links | BibTeX

A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability

Noh Seungmin ; Jeon, Sungwoong; Kim Eunhee; Oh Untaek; Park Danbi; Park Sun Hwa; Kim Sung Won; Pané Salvador; Nelson Bradley; Kim Jin-young; Choi Hongsoo;

A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability Journal Article

Small, 2022.

Abstract | Links | BibTeX

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks

Sato Yuya; Yamamoto, Hideaki; Kato Hideyuki; Tanii Takashi; Sato Shigeo; Hirano-Iwata Ayumi

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks Journal Article

2022.

Abstract | Links | BibTeX

Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array

Shimba Kenta; Asahina, Takahiro; Sakai Koji; Kotani Kiyoshi; Jimbo Yasuhiko

Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array Journal Article

Frontiers in Neuroscience, 2022.

Abstract | Links | BibTeX

Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics 2 electrophysiological phenotype of the A53T mutation

Hornauer Philipp; Prack, Gustavo; Anastasi Nadia; Ronchi Silvia; Kim Taehoon; Donner Christian; Fiscella Michele; Borgwardt Karsten; Taylor Verdon; Jagasia Ravi; Roqueiro Damian; Hierlemann Andreas;

Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics 2 electrophysiological phenotype of the A53T mutation Journal Article

bioRxiv, 2022.

Abstract | Links | BibTeX

Design strategies for controlling neuron-connected robots using reinforcement learning

Sawada, Haruto; Wake, Naoki; Sasabuchi, Kazuhiro; Takamatsu, Jun; Takahashi, Hirokazu; Ikeuchi, Katsushi

Design strategies for controlling neuron-connected robots using reinforcement learning Journal Article

arXiv, 2022.

Abstract | Links | BibTeX

Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays

Duru Jens; Küchler, Joël; Ihle Stephan Forró Csaba; Bernardi Aeneas; Girardin Sophie; Hengsteler Julian; Wheeler Stephen; János; Ruff Tobias; J ; Vörös

Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays Journal Article

2022.

Abstract | Links | BibTeX

Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons

McSweeney, Danny; Gabriel, Rafael; Jin, Kang; Pang, Zhiping P; Aronow, Bruce; Pak, ChangHui

Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons Journal Article

BioRxiv, 2022.

Abstract | Links | BibTeX

Autism genes converge on asynchronous development of shared neuron classes

Paulsen, Bruna; Velasco, Silvia; Kedaigle, Amanda J; Pigoni, Martina; Quadrato, Giorgia; Deo, Anthony J; Adiconis, Xian; Uzquiano, Ana; Sartore, Rafaela; Yang, Sung Min; Simmons, Sean K; Symvoulidis, Panagiotis; Kim, Kwanho; Tsafou, Kalliopi; Podury, Archana; Abbate, Catherine; Tucewicz, Ashley; Smith, Samantha N; Albanese, Alexandre; Barrett, Lindy; Sanjana, Neville E; Shi, Xi; Chung, Kwanghun; Lage, Kasper; Boyden, Edward S; andJoshua Levin, Aviv Regev Z; Arlotta, Paola

Autism genes converge on asynchronous development of shared neuron classes Journal Article

Nature, 602 , pp. 268–273, 2022.

Abstract | Links | BibTeX

68 entries « 1 of 2 »

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Would you like to learn more about MaxOne? Book a one-to-one call with one of our scientist to discuss how MaxWell Biosystems’ high-content electrophysiology solutions can bring new key insights to your project or request a quote.

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